Patterns of recurrence in oral tongue cancer with perineural invasion
نویسندگان
چکیده
منابع مشابه
A clinicopathological study of perineural invasion and vascular invasion in oral tongue squamous cell carcinoma.
The risk factors for recurrence of head and neck cancer are classified as being of high or intermediate risk. Those of intermediate risk include multiple positive nodes without extracapsular nodal spread, perineural/vascular invasion, pT3/T4 primary tumours, and positive level IV/V nodes. However, little evidence is available to validate these intermediate risk factors. We analyzed perineural/v...
متن کاملRisks and clinical implications of perineural invasion in T1-2 oral tongue squamous cell carcinoma.
BACKGROUND Risks of perineural invasion (PNI) in T1-2 oral tongue squamous cell carcinoma (SCC) have not been specifically elucidated. METHODS Pathological features, including PNI, were re-reviewed under regular hematoxylin-eosin staining in 190 patients with T1-2 oral tongue SCC. RESULTS Tumor thickness >5 mm, PNI(+), and lymphovascular invasion (+) independently predicted lymph node invol...
متن کاملInfluence of perineural invasion on survival and recurrence in patients with resected pancreatic cancer.
BACKGROUND Perineural invasion (PNI) has been reported as one of the sources of locoregional recurrence in resected pancreatic cancer (PC). However the impact of PNI in resected pancreatic cancer remains controversial. The purpose of this study was to determine the association between PNI status and clinical outcomes. METHODS Publications were identified which assessed prognostic significance...
متن کاملMandibular Canal Widening and Bell's Palsy: Sequelae of Perineural Invasion in Oral Cancer
Perineural invasion is an underrecognized route of metastatic spread along the nerve bundles within the nerve sheath into the surrounding tissues. It hinders the ability to establish local control as tumour cells can traverse along nerve tracts well beyond the extent of any local invasion rendering them inoperable and unresectable. Perineural invasion is a marker of poor prognosis. Oral submuco...
متن کاملEarly oral tongue cancer initially managed with surgery alone: Treatment of recurrence☆
Objective To report T1-2N0 tongue cancer recurrences initially treated with surgery alone. Methods Between 1990 and 2010, 27 patients at tertiary hospital referral center institution were treated with curative intent for locoregional recurrence after initial glossectomy with or without neck dissection for T1-2N0 tongue cancer. None had received adjuvant postoperative radiation as a component ...
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ژورنال
عنوان ژورنال: Head & Neck
سال: 2018
ISSN: 1043-3074
DOI: 10.1002/hed.25110